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Anthropometric measures of obesity as risk indicators for prediabetes. A systematic review and meta-analysis

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This systematic review and meta-analysis found that obesity, as measured by body mass index (BMI), waist circumference (WC), and waist to height ratio (WHtR), is significantly associated with an increased risk of prediabetes. However, WC may be the best indicator for predicting prediabetes. Further studies are needed to confirm these results and determine the most effective way to measure obesity as a risk factor for prediabetes.

Anthropometric measures of obesity as risk indicators for prediabetes. A systematic review and meta-analysis Read More »

Precision Nutrition Unveiled: Gene–Nutrient Interactions, Microbiota Dynamics, and Lifestyle Factors in Obesity Management

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This review highlights precision nutrition (PN) as an effective strategy for managing obesity by integrating gene-nutrient interactions, intestinal microbiota, and lifestyle factors. It emphasizes PN’s role in improving dietary quality and physical activity adherence, while also offering potential for long-term prevention of obesity and its related complications.

Precision Nutrition Unveiled: Gene–Nutrient Interactions, Microbiota Dynamics, and Lifestyle Factors in Obesity Management Read More »

COVID-19-Induced Diabetes Mellitus: Comprehensive Cellular and Molecular Mechanistic Insights

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This research paper explores the relationship between COVID-19 and diabetes mellitus, highlighting the need for further investigation into the long-term effects of the virus on glucose tolerance and insulin sensitivity. The authors suggest regular screening for diabetes in high-risk populations with a history of COVID-19 infection and potential therapeutic interventions to prevent new-onset diabetes.

COVID-19-Induced Diabetes Mellitus: Comprehensive Cellular and Molecular Mechanistic Insights Read More »

ACTION APAC: Understanding perceptions, attitudes and behaviours in obesity and its management across south and Southeast Asia

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To identify perceptions and attitudes among people with obesity (PwO) and healthcare professionals (HCPs) toward obesity and its management in nine Asia-Pacific (APAC) countries, a cross-sectional online survey was conducted among adult PwO with self-reported body mass index of ≥25 kg/m2 (≥27 kg/m2, Singapore), and HCPs involved in direct patient care.

ACTION APAC: Understanding perceptions, attitudes and behaviours in obesity and its management across south and Southeast Asia Read More »

A genomics perspective of personalized prevention and management of obesity

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This review explores personalized prevention and management of obesity through a nutrigenetics lens, highlighting how genetic variations influence responses to different macronutrients. It identifies potential targets for obesity management, including pathways related to circadian rhythm and cholesterol metabolism, and suggests the repurposing of the SYK inhibitor fostamatinib for treatment based on genetic profiles. The study also emphasizes the importance of understanding genetic factors in lifestyle changes for effective weight management.

A genomics perspective of personalized prevention and management of obesity Read More »

Genetic variant panel allows predicting both obesity risk, and efficacy of procedures and diet in weight loss

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This study evaluates the association of 102 genetic variants with body mass index (BMI) and weight loss treatment response in a multi-ethnic population. It identifies specific single nucleotide polymorphisms (SNPs) linked to increased BMI and varying efficacy of weight loss interventions, suggesting the potential for personalized weight management strategies based on genetic profiles.

Genetic variant panel allows predicting both obesity risk, and efficacy of procedures and diet in weight loss Read More »

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