This study evaluates the association of 102 genetic variants with body mass index (BMI) and weight loss treatment response in a multi-ethnic population. It identifies specific single nucleotide polymorphisms (SNPs) linked to increased BMI and varying efficacy of weight loss interventions, suggesting the potential for personalized weight management strategies based on genetic profiles.
The study aimed to determine if remission of type 2 diabetes (T2D) could be achieved through a low-energy total diet replacement in an Australian primary care setting. At 12 months, 56% of participants achieved T2D remission, with an average weight loss of 8.1%.
Diabetic foot ulcers (DFUs) are a common and serious complication of diabetes, leading to disabilities, reduced quality of life, and high costs. The pathophysiology of DFUs involves metabolic dysfunction, diabetic immunopathy, diabetic neuropathy, and angiopathy, which can lead to infections and other complications. Understanding and addressing these factors can help prevent and manage DFUs more effectively.
The pathophysiology of diabetic foot: a narrative review Read More »
This review highlights the effectiveness of precision nutrition in improving risk factors for obesity and type 2 diabetes by tailoring dietary recommendations to individual characteristics such as genetics and lifestyle. It suggests that this personalized approach may be a more effective strategy than conventional dietary interventions, which have shown inconsistent results.
Precision Nutrition to Improve Risk Factors of Obesity and Type 2 Diabetes Read More »
Diabetes Mellitus (DM) is a metabolic disorder that can lead to various complications, including anemia. Chronic hyperglycemia causes changes in red blood cells (RBCs) that make them more susceptible to being cleared from circulation. This review discusses the mechanisms behind these changes and their impact on microangiopathy in DM.
Pathophysiology of Red Blood Cell Dysfunction in Diabetes and Its Complications Read More »
The Korean Society for the Study of Obesity defined overweight as a BMI ≥23 kg/m2 and obesity as a BMI ≥25 kg/m2, based on a significant increase in obesity-related diseases. A waist circumference of ≥90 cm in men and ≥85 cm in women are defined as abdominal obesity, which is also correlated with obesity-related diseases.
Our study aimed to investigate people’s motivations for participating in weight loss trials and determine any relationship with gender.
Motivations for participation in weight loss clinical trials Read More »
The study investigates motivations for participating in weight loss clinical trials, highlighting gender differences in these motivations. Improved health is a common motivation for all participants, but males are more influenced by healthcare advice, while females are driven by family and aesthetic expectations. Understanding these differences aims to enhance recruitment strategies for male participants in future trials.
Motivations for participation in weight loss clinical trials Read More »
In recent years, endoscopic bariatric therapies have evolved as an effective, minimally invasive and durable therapeutic option for obesity. Metabolic–bariatric surgery remains the most effective and durable treatment for patients with severe obesity, with an average weight loss of 25%–30% after one year.
Current treatment landscape for obesity in Singapore Read More »
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