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Trends in the Prevalence of Cardiometabolic Multimorbidity in the United States, 1999–2018

The prevalence of cardiometabolic multimorbidity (co-existence of ≥1 cardiometabolic diseases) in the U.S. has been increasing significantly from 1999 to 2018, with a prevalence of 14.4% in 2017-2018. This trend was observed in both genders, most age groups, and non-Hispanic White people. The most common patterns were hypertension and diabetes, hypertension, diabetes, and CHD, and hypertension and CHD. This highlights the growing concern of cardiometabolic multimorbidity as a public health issue in the U.S.

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Personalized Type 2 Diabetes Management: An Update on Recent Advances and Recommendations

Recent guidelines for managing type 2 diabetes mellitus (T2D) emphasize a personalized approach over rigid treatment algorithms, aiming to enhance patient satisfaction, medication adherence, and overall health outcomes. This strategy involves tailoring treatment goals based on individual medical and patient factors, ultimately reducing costs and complications associated with diabetes management.

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Association between cardiometabolic disease multimorbidity and all-cause mortality in 2 million women and men registered in UK general practices

This study examined the association between cardiometabolic diseases (MI, stroke, and diabetes) and all-cause mortality in 2 million patients. Results showed that having all three conditions increased the risk of mortality, but this excess risk was not significantly greater than expected from the individual diseases. The presence of other comorbidities also contributed to the excess mortality risks associated with cardiometabolic disease multimorbidity.

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COVID-19 and diabetes mellitus: from pathophysiology to clinical management

The research highlights the increased severity of COVID-19 in patients with diabetes mellitus, noting that hyperglycaemia may worsen outcomes by affecting immune responses. It suggests that insulin should be the primary treatment for managing acute glycaemia in these patients, while the effects of glucose-lowering medications like DPP4 inhibitors and SGLT2 inhibitors remain uncertain. Further investigation into the management of diabetes in the context of COVID-19 is needed.

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